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3.6 Expression profile of key pathway proteins The key pr o teins predicted in top canonical pathway, AhR and Heat shock protein (HSP)90 validated by western blot (Figures 8C, D) which corroborated the LC-MS/MS data

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Numerous studies have demonstrated that impeding IGF-1R by inhibitors or monoclonal antibodies curtails the expansion and invasion of tumor cells, augments apoptosis, and heightens the vulnerability of GBM cells to chemotherapy and radiation

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These effects of the perinatal environment on GR can be imposed long-term via changes to the epigenome